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Date of Report:
10/08/2003
Author:
Laurence Peiperl, MD, Medical Editor
Source:
AETC National Resource Center
FluMist, a recently approved live attenuated influenza vaccine (LAIV), which is given intranasally, should not be used in people with HIV infection.(
1
) Further, no data are available assessing the risk for transmission of LAIV from vaccine recipients to immunosuppressed contacts. In the absence of such data, and because of the theoretical risk that a live, attenuated vaccine virus could be transmitted to the immunosuppressed person and cause disease, use of inactivated influenza vaccine (which is given intramuscularly) is preferred for vaccinating household members, health-care workers, and others who have close contact with immunosuppressed persons.
References
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Scott A. Harper, Keiji Fukuda, Nancy J. Cox, Carolyn B. Bridges. Using Live, Attenuated Influenza Vaccine for Prevention and Control of Influenza. MMWR September 26, 2003;52(RR13):1-8
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