Antiretroviral Drug Resistance Testing in Adult HIV-1 Infection: 2008 Recommendations of an International AIDS Society-USA Panel
Published Date: 07/15/2008
Source: International Antiviral Society-USA
Authors: Martin S. Hirsch; Huldrych F. Günthard; Jonathan M. Shapiro; Françoise Brun-Vézinet; Bonaventura Clotet; Scott M. Hammer; Victoria A. Johnson; Daniel R. Kuritzkes, MD; John W. Mellors; Deenan PIllay; Patrick G. Yeni; Donna Jacobsen and Douglas D. Richman
Antiretroviral Drug Resistance Testing in Adult HIV-1 Infection: 2008 Recommendations of an International AIDS Society-USA Panel PDF [457K]
Clinical Infectious Diseases
Abstract: Resistance to antiretroviral drugs remains an important limitation to successful human immunodeficiency virus type 1 (HIV-1) therapy. Resistance testing can improve treatment outcomes for infected individuals. The availability of new drugs from various classes, standardization of resistance assays, and the development of viral tropism tests necessitate new guidelines for resistance testing. The International AIDS Society-USA convened a panel of physicians and scientists with expertise in drug-resistant HIV-1, drug management, and patient care to review recently published data and presentations at scientific conferences and to provide updated recommendations. Whenever possible, resistance testing is recommended at the time of HIV infection diagnosis as part of the initial comprehensive patient assessment, as well as in all cases of virologic failure. Tropism testing is recommended whenever the use of chemokine receptor 5
antagonists is contemplated. As the roll out of antiretroviral therapy continues in developing countries, drug resistance monitoring for both subtype B and non-subtype B strains of HIV will become increasingly important.
Browse similar resources:
|Materials Usage Guidelines|close
We ask that those wishing to use the materials found on the AETC NRC website honor the following guidelines:
- Slide sets and other materials that appear on the AETC NRC website are intended for public use, unless otherwise noted.
- You may use or present a slide set or other material in its entirety if you credit the author and source of the material.
- Similarly, you may incorporate selected slides or resources from the AETC NRC website into another public presentation if you credit the author and/or source of the materials.
- If you use materials from the AETC NRC website in preparing other presentations or materials, please Include an appropriate reference citation.
- Do not publish or post materials found on the AETC NRC site without permission from their creators or copyright holders.
- For examples of appropriate citation, see our Using and Adapting Slides frequently asked questions.
Copyright 2013, the AIDS Education & Training Centers National Resource Center, unless otherwise noted. All rights reserved. Email email@example.com with questions, comments, or problems. See disclaimer for usage guidelines.