- Section 2: Testing and Assessment
- Initial History
- Initial Physical Examination
- Initial and Interim Laboratory and Other Tests
- Interim History and Physical Examination
- HIV Classification: CDC and WHO Staging Systems
- CD4 and Viral Load Monitoring
- Risk of HIV Progression/Indications for ART
- Early HIV Infection
- Expedited HIV Testing
- Resistance Testing
- Karnofsky Performance Scale
- Occupational Postexposure Prophylaxis
- Nonoccupational Postexposure Prophylaxis
- Preventing HIV Transmission/Prevention with Positives
- Immunizations for HIV-Infected Adults and Adolescents
- Preventing Exposure to Opportunistic and Other Infections
- Opportunistic Infection Prophylaxis
- Latent Tuberculosis Infection
- Smoking Cessation
- Abnormalities of Body-Fat Distribution
- Insulin Resistance, Hyperglycemia, and Diabetes on Antiretroviral Therapy
- Coronary Heart Disease Risk
- Renal Disease
- Immune Reconstitution Inflammatory Syndrome
- Anal Dysplasia
- Candidiasis, Oral and Esophageal
- Candidiasis, Vulvovaginal
- Cervical Dysplasia
- Cryptococcal Disease
- Cytomegalovirus Disease
- Gonorrhea and Chlamydia
- Hepatitis B Infection
- Hepatitis C Infection
- Herpes Simplex, Mucocutaneous
- Herpes Zoster/Shingles
- Kaposi Sarcoma
- Molluscum Contagiosum
- Mycobacterium avium Complex Disease
- Mycobacterium tuberculosis
- Pelvic Inflammatory Disease
- Pneumocystis Pneumonia
- Progressive Multifocal Leukoencephalopathy
- Seborrheic Dermatitis
Preventing HIV Transmission/Prevention with Positives
Publish date: April 2014
In recent years, the rate of new HIV infections in the United States has remained stable in the range of 50,000 per year. Antiretroviral therapy (ART) not only improves the health of individuals on treatment but also substantially reduces the risk of transmitting HIV infection. It has become a critical component of efforts to prevent new infections (hence the saying, "treatment is prevention"), but it is not fully effective. Additionally, it remains true that only a minority of persons living with HIV infection in the United States is taking ART and a smaller proportion has maximal suppression of HIV viral load. Thus, behavioral and other risk-reduction interventions remain important aspects of HIV prevention. This chapter will focus primarily on interacting with patients around transmission risk behaviors, with the goal of reducing HIV transmission. This aspect of care is often referred to as "prevention with positives" (PWP).
For many years HIV, prevention efforts have been targeted primarily at HIV-uninfected individuals, but HIV-infected persons also must be a crucial focus for HIV prevention. Helping HIV-infected persons reduce their risks of transmitting HIV to others is an important aspect of medical care for HIV-infected patients. Most people with HIV infection want to prevent others from being infected with HIV, but they may practice sexual or injection-drug behaviors that put others at risk of infection.
Health care providers for HIV-infected patients can play a crucial role in prevention efforts, including but not limited to provision and monitoring of ART. Many HIV-infected individuals report that they want to discuss prevention with their health care providers; however, (according to multiple studies), one third to three fourths of HIV medical providers do not ask their patients about sexual behavior or drug use. Each patient visit presents an opportunity to provide effective prevention interventions, even in busy clinical settings.
It is clear that information alone, especially on subjects such as sexual activity and drug use, cannot be expected to change patients' behavior. However, health care providers can help patients understand the transmission risk of certain types of behavior and help patients establish personal prevention strategies (sometimes based on a harm-reduction approach) for themselves and their partners. Some patients may have difficulty adhering to their safer sex goals. In these cases, referrals to mental health clinicians or other professional resources such as prevention case management may be helpful.
Patient-education needs are variable and must be customized. Providers must assess the individual patient's current level of knowledge as part of developing a prevention plan. All the information that a patient needs cannot be covered during a single visit. A patient's prevention strategy should be reinforced and refined at each visit with the clinician. Clinicians also should ask patients questions to determine life changes (e.g., a new relationship, a breakup, or loss of a job) that may affect the patient's sexual or substance-use practices. If the patient can read well, printed material can be given to reinforce education in key areas, but it cannot replace a direct conversation with the clinician.
Note: The U.S. Department of Health and Human Services is expected to publish guidelines on HIV prevention in the near future; those may contain recommendations that differ from the ones presented here.
National Prevention Intervention Efforts
The U.S. Centers for Disease Control and Prevention (CDC) has developed a prevention approach called High-Impact Prevention that focuses on populations at greatest risk of acquiring or transmitting HIV, using proven, scalable, and cost-effective interventions. Proven interventions include:
- HIV testing and linkage to care
- Prevention programs for people living with HIV and their partners
- Prevention programs for people at high risk of HIV infection
- Access to condoms and sterile syringes
- Screening and treatment for sexually transmitted diseases (STDs)
- Substance abuse treatment
The CDC has identified a number of evidence-based behavioral prevention interventions aimed at persons with HIV infection that meet criteria for efficacy and scientific rigor. These are conducted on the individual, group, or community level, and a number of them may be implemented in the treatment setting. A Compendium of these interventions can be accessed online at the CDC website. Training and educational materials for effective intervention models can be found on the CDC-supported Diffusion of Effective Behavioral Interventions (DEBI) website.
Among the many examples of Prevention Intervention Programs with Demonstrated Efficacy in Treatment Settings on the CDC website are the following:
- Options/Opciones Program: The program features brief, 5-10 minute patient-centered discussions between patients and providers at each clinic visit using motivational interviewing techniques. Providers evaluate sexual and drug-use behaviors, assess the patient's readiness to change, and elicit methods from the patient on moving toward and maintaining safer behaviors. The provider and the patient develop an individually tailored plan, which the provider writes out on a prescription pad and gives to the patient.
- Partnership for Health: This intervention involves brief, 3-5 minute, one-on-one counseling sessions between the provider and the patient on self-protection, partner-protection, and disclosure. The approach features loss-framed messages that emphasize the risks or negative consequences of risky behavior. The provider then helps the patient develop a plan for risk reduction.
- Positive Choice - Interactive Video Doctor: This program involves an approximately 24-minute session during which HIV-infected patients complete the Positive Choice risk assessment on a laptop computer while waiting for scheduled visits with their providers. Based on the risk-assessment results, a video clip appears with the actor-portrayed Video Doctor who delivers interactive risk-reduction messages that are tailored to the patient's gender, risk profile, and readiness to change. The messages are delivered with motivational interviewing principles, using a patient-centered, empathetic and nonjudgmental approach. After the video session, the computer prints out an individualized educational sheet for the patient and an assessment sheet for the patient and the provider to use for follow-up.
The U.S. Preventive Services Task Force (USPSTF) has recommended high-intensity behavioral counseling to prevent STDs (including HIV) in persons at risk of these infections; these approaches also are being used in persons with HIV infection to reduce their risk of transmitting HIV. Effective high-intensity behavioral counseling typically comprises multiple sessions with either groups or individuals. Examples of these are included amongst the models presented on the CDC and DEBI websites.
Strategies for Brief, Effective Interventions by Providers
A number of strategies have been shown to be more effective than providing information alone. Effective and brief provider-initiated interventions often include the following elements:
- Establish rapport and provide services in an understanding, nonjudgmental manner. Patient educators, nurses, peer counselors, social workers, and mental health providers may be effective in discussing prevention strategies with patients.
- Conduct a quick, detailed behavioral risk assessment:
- See the key areas of risk assessment and intervention listed in Table 1, below.
- Assess where the patient's risk behavior lies along the risk continuum (described in chapter Smoking Cessation).
- Correct misinformation and answer questions.
- Assess the patient's readiness for behavior change (see "Stages of Change model," below).
- Screen for and treat STDs: a positive STD test result can be a biologic marker of behavioral risk, and STDs may facilitate HIV transmission (see chapter Initial and Interim Laboratory and Other Tests).
- Supply medications, condoms, and lubricant as needed.
- Assess the patient's readiness for change and approach any high-risk behavior in a step-wise manner, recognizing when the patient is ready for next steps. Such interventions may be carried out for 5-10 minutes per visit over a series of visits. The "Stages of Change" model and appropriate strategies include the following:
- Precontemplation: The patient is not ready to change; reassess at subsequent visits.
- Contemplation: The patient is considering a change in the future; discuss and help the patient to identify concrete next steps, such as a date for initiating change.
- Preparation: The patient is ready to change soon; discuss a concrete action plan and connect the patient with appropriate resources as needed.
- Action: The patient is actively engaged in changing behavior; continue to discuss and address challenges; offer encouragement.
- Maintenance: The patient has made behavioral changes; continue to discuss and address challenges, offer encouragement and congratulations.
- (Relapse): The patient has relapsed to previous risky behaviors; recognize the triggers and difficulties the patient had with maintenance and offer support and encouragement to try again when the patient is ready.
- Customize messages, as each individual patient's needs are variable.
- Understand that patients often have competing priorities and pressures involving mental health needs, relationships, finances, housing, employment, and other issues that may result in risky sexual and drug-use behaviors.
Prevention with Positives: Key Areas of Assessment and Intervention
These topics should be explored over time. Some sample questions and areas for intervention are presented in Table 1. More detailed discussions of topics follow this table.
|Topic||Sample Questions, Assessment, and Plan|
|General Risk Assessment||Subjective/objective questions to ask: |
Assessment and plan:
|Sexual Practices||Subjective/objective questions to ask: |
See below for more on partner notification.
Assessment and plan:
|Partner Notification||Subjective/objective questions to ask: |
Assessment and plan: ways to offer help for disclosure
|Antiretroviral Therapy (ART)|
|STD Screening and Treatment|
Although hepatitis B and hepatitis C are not known to increase the risk of HIV infection, they may be transmitted sexually, and persons with risk factors (particularly MSM with risky sexual practices) should be screened regularly (see chapter Initial and Interim Laboratory and Other Tests).
* NAAT is not yet approved for this indication by the U.S. Food and Drug Administration (FDA), though there is evidence that NAAT can accurately diagnose pharyngeal and rectal gonorrhea and chlamydia infections. Many local public health departments and other laboratories have received Clinical Laboratory Improvement Amendments (CLIA) waivers to perform these tests.
|Drug and Alcohol Risk Assessment||Subjective/objective questions to ask: |
See below for follow-up on needle-sharing practices.
Assessment and plan:
|Needle-Use Practices||Subjective/objective question to ask: |
Assessment and plan:
|Mental Health Assessment|
Mental illnesses such as bipolar disorder, depression, and post-traumatic stress disorder can increase the chances of risky sexual and drug-use behaviors. Ask about mental health illnesses directly and pay attention to any symptoms that may indicate a psychiatric illness (e.g., manic episodes, depressive episodes, hallucinations).
Subjective/objective questions to ask:
Assessment and plan:
See section Neuropsychiatric Disorders for more information.
Subjective/objective questions to ask:
For women of childbearing potential:
For men with female sex partners:
Assessment and plan:
Sexual Transmission and Prevention of HIV
Begin the education process by learning what the patient and his or her immediate family members (if the family is aware of the patient's HIV status) believe about HIV transmission. Also be sure the patient understands how the virus is not transmitted (e.g., via sharing plates and eating utensils or using the same bathrooms) to allay any unnecessary fear.
Advise the patient not to share toothbrushes, razors, douche equipment, or sex toys to avoid transmitting HIV via blood or sexual secretions. This also will help prevent the transmission of other bloodborne or sexually transmitted diseases, including hepatitis C, from coinfected patients. The patient should not donate blood, plasma, tissue, organs, or semen because these can transmit HIV to the recipient.
There is no reason why a person with HIV cannot have an active, fulfilling, and intimate sex life. However, the patient must be counseled properly about the risk of transmission. This discussion between the provider and patient should be client centered. This means that the provider should let the patient guide the discussion, starting from the patient's current point of knowledge and practice, always addressing any presenting concerns the patient may have prior to proceeding with a discussion about sexual transmission and risk. The provider should ask open-ended questions, in a nonjudgmental manner, to elicit information about the patient's relationships, sexual behaviors, and current means of reducing transmission risk.
It is important to recognize that not every patient seeks the complete elimination of risk (e.g., via abstinence) but rather a reduction in risk, chosen after the options are discussed with the provider. The clinician may help the patient select and practice behaviors that are likely to be less risky. There are many methods for reducing risk, including the following:
- Disclosing HIV status
- Maintaining maximal suppression of HIV through ART
- Reducing the number of sex partners
- Using condoms, particularly for anal or vaginal intercourse (insertive or receptive)
- Avoiding drug use in conjunction with sex
- Using adequate lubrication to avoid trauma to genital or rectal mucosa
If the patient requires more extensive counseling to support behavioral changes, the provider should refer the patient to support groups or prevention case management to meet those needs. Certainly, if the patient is dealing with a dual or triple diagnosis (including substance abuse or mental illness), a referral to address those needs is indicated.
Partner Notification and Partner Services
A good way to begin a discussion about HIV prevention and transmission is with an inquiry about any previous experiences disclosing to partners. The provider then can ask whether the patient currently has a need to disclose to one or more partners and whether he or she is ready and motivated to share information about HIV status. The provider should prompt patients to consider several questions about disclosure, including how they might approach the discussion, how their partners might react, what information they might offer their partners, whether partners are likely to keep their status confidential, and whether they have any concerns about personal safety (e.g., owing to fear of a violent reaction). If patients fear violence or retaliation or are not ready to share their status but want their partners to know, the provider may offer assistance with partner services, for example through the local health department, through which partners can be notified and linked to services in a confidential manner. As an alternative, patients may want the provider to talk with their partners, and that option can be offered as well. See the CDC website (www.cdc.gov/nchhstp/partners/Partner-Services.html) for information on partner services.
ART that results in maximal HIV suppression is an important means of HIV prevention. In serodiscordant heterosexual couples, one randomized controlled trial showed that ART reduced the risk of sexual transmission of HIV by 96%. Similar study data for MSM, injection drug users, and other HIV risk groups do not exist, but multiple other lines of evidence suggest that effective ART sharply reduces risk of HIV transmission. Thus, ART should be offered to all HIV-infected persons, both to benefit their own health and to reduce risk of HIV transmission to others, as recommended in HHS guidelines. Support patients' adherence to ARVs in order to optimize the effectiveness of ART as both treatment and prevention.
Note that ART does not eliminate HIV transmission risk. In some individuals, there can be substantial discrepancies between HIV RNA levels in the serum and the sexual fluids. There have been case reports of HIV transmission from HIV-infected individuals who had maximal virologic suppression on ART. Thus, other behavioral and biologic risk-reduction approaches (e.g., screening for and offering interventions or treatment for risky sexual behaviors, substance use, depression, STDs, and other factors listed in Table 1) are important aspects of prevention in patients taking ART, as in patients not taking ART.
Helping Patients Reduce the Risk of Sexual Transmission
Standard Condom Use
Make sure that the patient understands how HIV is transmitted and which types of sexual acts are more and less risky than others. For vaginal or anal sex, correct use of latex or polyurethane condoms reduces the risk of HIV transmission considerably. Patients should be encouraged to use condoms as much as possible. For HIV-infected individuals, condom use is effective in reducing the risk of contracting another illness (such as hepatitis C or another STD) and the (apparently low) risk of becoming reinfected with another strain of HIV. It should be noted that condoms are less effective in reducing the transmission of organisms such as human papillomavirus (HPV) and HSV, which may result from viral shedding from skin. In the event of allergy to latex or other difficulty with latex condoms, polyurethane male or female condoms may be substituted. "Natural skin" or "lambskin" condoms are not recommended for HIV prevention.
Of course, condoms must be used correctly to be highly effective in preventing HIV transmission. Be sure that the patient knows exactly how to use a condom. Table 2, in the Appendix, provides instructions for condom use.
Advise patients to avoid using nonoxynol-9 (N-9) spermicides. Data suggest that N-9 may increase risk of HIV transmission during vaginal intercourse and can damage the rectal lining. N-9 never should be used for anal intercourse.
For patients who complain about lack of sensitivity with condom use, the following techniques may help:
- Apply a drop of lubricant inside the condom (not more, because it increases the risk that the condom will come off).
- Use polyurethane condoms instead of latex because they conduct heat and may feel more natural.
- Use insertive (female) condoms, which are not as restrictive to the penis.
- Use specially designed condoms that do not restrict the top of the penis (e.g., Inspiral, Xtra Pleasure).
For patients who are unable or unwilling to use condoms, the following suggestions may help reduce HIV transmission risk:
- Use plenty of lubricant to reduce friction and microtrauma, which create portals of entry for the virus.
- Avoid spermicides that damage the vaginal or anorectal linings.
- Avoid douching products.
- Avoid recreational drugs, especially methamphetamine, that impair the ability to maintain "safer" sexual behaviors.
- Avoid the use of drugs such as nitrates (poppers) that enhance blood flow to the genitals.
Insertive (Female) Condom Use
The insertive "female" condom may be used for vaginal or anal intercourse. It is a thin polyurethane pouch with a flexible ring at the opening, and another unattached flexible ring that sits inside the pouch to keep it in position in the vagina (for use in the anus, the inner ring must be removed and discarded). The female condom may be an option for women whose male partners will not use male condoms or for couples who do not like standard condoms. Female condoms are more expensive than male condoms, but may be procured at a lower cost at some health departments or Planned Parenthood clinics. They generally are less well known to patients and may be unacceptable to some women whose culture or religion prohibits or discourages touching one's own genitals. Note that the female condom cannot be used at the same time as a male condom.
Be sure the patient knows how to use the insertive condom before she or he needs it; after teaching, encourage practice when alone at home and unhurried. Women who have used the diaphragm, cervical cap, or contraceptive sponge may find it easy to use the female condom. Illustrated directions are included in each box of insertive condoms. Instructions on the use of insertive condoms are provided in Table 3, in the Appendix.
Although there is evidence that some people have become infected through receptive oral sex, the risk of HIV transmission via oral sex, in general, is much lower than the risk of transmission by vaginal or anal sex. Thus, most public health and prevention specialists focus their attention on riskier sexual and drug-use behaviors. However, because HIV transmission can occur with oral sex, clinicians should address this issue with patients and help them make informed decisions about risk reduction. Sores or lesions in or around the mouth or on the genitals may increase the risk of HIV transmission, as may a concurrent STD. Patients (and their partners) should avoid oral-genital contact if they have these conditions. Similarly, patients and partners can further reduce risk by not brushing or flossing teeth before oral sex. Individuals who wish to further reduce the risk of HIV transmission during oral sex may use barriers such as condoms, dental dams, and flexible plastic nonporous kitchen wrap.
Individuals who smoke crack cocaine often develop open burns, cracked lips, or damaged mucous membranes inside the mouth and thus may be at elevated risk of HIV transmission via oral sex. HIV-infected crack users should be counseled about the risk of transmitting HIV to uninfected partners through those portals of entry during oral sex and should receive risk-reduction counseling. In addition, they (or their partners) may benefit from techniques such as insulating the end of the crack pipe to reduce burns while smoking (e.g., with a rubber band or spark plug cap) and avoiding the brittle or sharp-edged copper scrubbing pads used as screens in the crack pipe.
Influence of Substance Use on Sexual Behavior
Alcohol and drug use can contribute significantly to the risk of sexual transmission of HIV, because of behavioral disinhibition. While intoxicated, substance users may, for example, forgo condom use, practice riskier sexual behaviors, have multiple partners, or use erectile dysfunction agents to sustain sexual activity. Addressing substance use issues is an important aspect of PWP. Patients should be assessed for HIV transmission risks associated with alcohol and injection or noninjection drug use, including crystal methamphetamine, in the context of their sexual behaviors (for injection drug use, see below). As always, it is important to approach the patient in a nonjudgmental manner. If alcohol or other drugs are posing barriers to practicing safer behaviors, the provider should counsel the patient to reduce or avoid substance use before engaging in sex, or refer the patient to prevention case management for more specialized risk reduction. Often, the provider can help the patient identify methods for reducing HIV transmission risk, including means that do not require abstaining from alcohol and drug use.
Injection Drug Use and Prevention of HIV
Clinicians should discuss substance use, including steroid use, and reinforce the patient's understanding of the adverse effects that these drugs can have on the body and the immune system. Assess whether referral for treatment is appropriate, and be knowledgeable about referral resources and mechanisms. If the patient is using injection drugs (including steroids and other hormones), emphasize the fact that HIV is readily transmitted by sharing needles and other injection equipment and that reusing or sharing needles and syringes can cause additional infections (e.g., endocarditis, hepatitis C). Assess the patient's readiness to change his or her drug injection practices, and refer to drug treatment programs as appropriate. Refer to an addiction counselor for motivational interviewing or other interventions, if available. After completion of substance abuse treatment, relapse prevention programs and ongoing support will be needed. If the patient continues to use needles, discuss safer needle-use practices (Table 1) and consider referral to a syringe service (needle exchange) program, if one is available, so that syringes and needles are not reused. A partial listing of needle exchange sites may be found on the North American Syringe Exchange Network website at www.nasen.org, although many states either do not have facilities or are prohibited from listing them. Local harm-reduction activists may be aware of specific programs for obtaining clean needles and syringes. Patient-education flyers on safer injection practices, safer stimulant use, overdose prevention, and other topics are available on the Midwest AIDS Education and Training Center website (www.uic.edu/depts/matec/resource.html).
Noninjection Drug Use and Prevention of HIV Transmission
Exposure to HIV through contaminated blood may occur with the use of noninjection drugs; for example, by sharing cocaine straws or sniffers through which cocaine is inhaled. These straws easily can penetrate fragile nasal mucosa and become contaminated with blood from one user before being used by another individual, who may then experience mucous membrane exposure or even a cut or break in the mucous membrane from the bloody object. Straws or sniffers should not be shared.
Tattoo, Piercing, and Acupuncture Equipment
Patients should be aware of the risk of contamination of tattoo equipment, inks, and piercing equipment, and they should avoid situations wherein they might either transmit HIV or pick up other bloodborne pathogens. Acupuncturists generally use sterile needles, but clients should verify that before using their services.
Perinatal HIV Transmission
HIV-infected women can have healthy pregnancies, with good health outcomes for both mother and baby. For this to occur, women must know their HIV status as early as possible, preferably before becoming pregnant, and must receive effective ART. Although intervention to reduce the risk of perinatal infection is most effective if begun early in pregnancy, or preferably before pregnancy, it may be beneficial at any point in the pregnancy, even as late as during labor. For further information, see chapter Reducing Maternal-Infant HIV Transmission.
Preexposure Prophylaxis (PrEP)
Preexposure prophylaxis (PrEP) refers to the use of oral or topical ARVs before HIV exposure with the goal of preventing HIV infection. Studies have evaluated PrEP strategies using either oral tenofovir + emtricitabine (Truvada), oral tenofovir, or vaginal tenofovir to prevent sexual acquisition of HIV in MSM and high-risk heterosexually active women and men. Most have shown efficacy (ranging from about 40% to 75%) in reducing infection risk, but two others have not demonstrated protective benefit. A study of PrEP using tenofovir in injection-drug users also showed a reduction in HIV infections in the tenofovir group (a 49% reduction in incidence). In all studies, the effectiveness of PrEP has been strongly related to the study participants' adherence to the PrEP medication. It should be noted that, in these PrEP studies, the ARV prophylaxis was given in conjunction with other risk-reduction interventions, including counseling, condom provision, and STD testing and treatment.
The CDC has issued interim guidelines on the use of oral tenofovir-emtricitabine as PrEP in MSM, heterosexually active adults, and injection-drug users (see "References," below); these guidelines offer recommendations for PrEP screening and use, as well as ongoing monitoring for adherence, safety, and HIV infection. They emphasize that PrEP should be delivered in the context of a comprehensive package of health and prevention services. In 2012, the FDA approved the fixed-dose combination tenofovir/emtricitabine (Truvada) to reduce the risk of sexually acquired HIV-1 in adults at high risk; it has not yet approved an indication for PrEP in injection-drug users.
U.S. Public Health Service (PHS) guidelines for PrEP use are currently in development.
Postexposure Prophylaxis for Nonoccupational HIV Exposure
Postexposure prophylaxis (PEP) may be considered for certain sexual exposures, sexual assaults, and other nonoccupational exposures to HIV. As with occupational PEP, a risk assessment must be completed and PEP medications, if indicated, must be started as soon after exposure as possible. The risks and toxicities of ARV drugs must be weighed against potential benefits, and the client's informed consent must be obtained. For further information, see chapter Nonoccupational Postexposure Prophylaxis.
Table 2. Instructions for Use of Standard Condoms
- Use a new latex or polyurethane condom with each act of sex (oral, anal, or vaginal). Make sure that the condom is undamaged, and that its expiration date has not passed.
- Carefully handle the condom to avoid damage (e.g., from fingernails, teeth).
- Being sure that the condom roll faces out, unroll the condom onto the erect penis before any genital contact with partner.
- Ensure that the tip of the condom is pinched when applying it to the top of the penis, to eliminate air in the tip that could cause breakage during ejaculation.
- Use only water-based lubricants with latex condoms. Oil-based lubricants (such as mineral oil, cooking oil, massage oil, body lotion, and petroleum jelly) can weaken latex or cause it to break, although they are fine with the use of polyurethane condoms. Adequate lubrication during intercourse helps reduce the risk of condom breakage.
Table 3. Instructions for Use of Insertive (Female) Condoms
- Open the pouch by tearing at notched edge of packet, and take out the female condom. Be sure that the lubricant is evenly distributed on the inside by rubbing the outsides together.
- Find a comfortable position, such as standing with one foot on a chair, sitting with knees apart, or squatting. Be sure the inner ring is inside, at the closed end of the pouch.
- Hold the pouch with the open end hanging down. While holding the outside of the pouch, squeeze the inner ring with your thumb and middle finger. Still squeezing, spread the labia with your other hand and insert the closed end of the pouch into the vagina.
- Now, put your fingers into the pouch itself, which should be inside the vagina, and push the inner ring and the pouch the rest of the way up into the vagina with your index finger. Check to see that the front side of the inner ring is just past the pubic bone. The back part of the inner ring should be up behind the cervix. The outer ring and about an inch of the pouch will be hanging outside the vagina.
- Until you and your partner become comfortable using the female condom, use your hand to guide the penis into the vagina, keeping it inside the pouch. If, during intercourse, the outer ring is pushed inside the vagina, stop, remove the female condom, and start over with a new one. Extra lubricant on the penis or the inside of the female condom may help keep this from happening.
- After intercourse, take out the condom by squeezing and twisting the outer ring to keep the semen inside the pouch. Throw away in a trash can; do not flush. Do not reuse.
- More information is available on the Planned Parenthood website.
- Remove the inner ring and discard it. Put the female condom on the penis of the insertive partner and insert the condom with the penis, being careful not to push the outer ring into the rectum. The outer ring remains outside the anus, for ease of removal after ejaculation.
- Centers for Disease Control and Prevention. Compendium of Evidence-Based HIV Behavioral Interventions. Accessed December 1, 2013.
- Centers for Disease Control and Prevention. High-Impact HIV Prevention: CDC's Approach to Reducing HIV Infections in the United States. Atlanta: U.S. Centers for Disease Control and Prevention; August 2011. Accessed December 1, 2013.
- Centers for Disease Control and Prevention. Interim guidance for clinicians considering the use of preexposure prophylaxis for the prevention of HIV infection in heterosexually active adults. MMWR Morb Mortal Wkly Rep. 2012 Aug 10;61(31):586-9.
- Centers for Disease Control and Prevention. Interim Guidance: Preexposure Prophylaxis for the Prevention of HIV Infection in Men Who Have Sex with Men. MMWR Recomm Rep. 2011 Jan 28;60(RR-3):65-69. Accessed December 1, 2013.
- Centers for Disease Control and Prevention. Recommendations for partner services programs for HIV infection, syphilis, gonorrhea, and chlamydial infection. MMWR Recomm Rep. 2008 Nov 7;57(RR-9):1-83; quiz CE1-4.
- Centers for Disease Control and Prevention. Sexually Transmitted Diseases Treatment Guidelines, 2010. MMWR 2010 Dec 17; 59 (No. RR-12):1-110. Accessed December 1, 2013.
- Centers for Disease Control and Prevention (CDC); Health Resources and Services Administration; National Institutes of Health; HIV Medicine Association of the Infectious Diseases Society of America. Incorporating HIV prevention into the medical care of persons living with HIV. MMWR Recomm Rep. 2003 Jul 18;52(RR-12):1-24.
- Cohen MS, Chen YQ, McCauley M, et al.; HPTN 052 Study Team. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med. 2011 Aug 11;365(6):493-505.
- Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of Health and Human Services. Accessed December 1, 2013.
- Richardson JL, Milam J, McCutchan A, et al. Effect of brief safer-sex counseling by medical providers to HIV-1 seropositive patients: a multi-clinic assessment. AIDS. 2004 May 21;18(8):1179-86.
- U.S. Department of Health and Human Services, Health Resources and Services Administration. A Guide to Primary Care for People with HIV/AIDS, 2004 Edition. Washington: U.S. Department of Health and Human Services; 2004.
- U.S. Department of Veterans Affairs. Prevention for Positives. In: Primary Care of Veterans with HIV. April 2009. Accessed December 1, 2013.
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Abbreviations for Dosing Terminology
- twice daily
- twice weekly
- intramuscular (injection), intramuscularly
- intravenous (injection), intravenously
- oral, orally
- Q2H, Q4H, etc.
- every 2 hours, every 4 hours, etc.
- every morning
- once daily
- every hour
- every night at bedtime
- four times daily
- every other day
- every evening
- three times daily
- three times weekly