These slides were developed using the Guidelines for Prevention and Treatment of Opportunistic Infections among HIV-Infected Adults and Adolescents prepared by the U.S. Centers for Disease Control and Prevention, the National Institutes of Health, and the HIV Medicine Association/Infectious Diseases Society of America, and published in July 2013. The section on Mucocutaneous Candidiasis was updated in November 2014. The intended audience is clinicians involved in the care of patients with HIV. 130 slides. Topics covered include Pneumocystis jiroveci pneumonia, Mucocutaneous candidiasis, Cryptococcosis, Histoplasmosis, Coccidioidomycosis, Aspergillosis.