About 30% of people receiving care and treatment for HIV infection have major depression. But is it best to conceptualize major depression as a mental illness or a medical illness? If you wake up in a bad mood but your body feels fine, you are very unlikely to have major depression. Physical symptoms, such as severe fatigue and disturbances of sleep and appetite, are part of the diagnostic criteria for major depression, and other physical complaints, such as dizziness, palpitations and gastrointestinal disturbances, are very common.
This was an open-label study. It evaluated the renal safety of elvitegravir/cobicistat/emtricitabine/tenofovir (Stribild, or the "quad" pill) and cobicistat. For those patients with mild-to-moderate renal impairment (estimated glomerular filtration rate [eGFR]: 50 to <90 mL/min).