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Step 5: Effective Drug Treatment of HIV

See also Antiretroviral Therapy, Adherence, and Initiating Treatment

Active Resources: 70

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Articles: 9

  • CROI 2017: Failure of Dolutegravir Monotherapy

    April 17, 2017

    • Susa Coffey, MD, AETC National Coordinating Resource Center, UCSF Center for HIV Information

    Leading up to this year, some researchers and clinicians had optimistically viewed dolutegravir an invincible ARV, a drug so mighty that it was unlikely to fail, and even more unlikely to be victim to emergent resistance mutations. Two presentations at CROI demonstrated the...

  • Efavirenz, Dolutegravir, and Darunavir: Pharmacokinetics during Pregnancy

    April 12, 2016

    Three studies presented at the 2016 Conference on Retroviruses and Opportunistic Infections (CROI) explored the pharmacokinetics of antiretrovirals administered during pregnancy. These studies support the use of standard-dose efavirenz, once-daily dolutegravir, and BID ritonavir-boosted...

  • Switching from TDF/FTC to TAF/FTC

    March 18, 2016

    • Susa Coffey, MD, AETC National Coordinating Resource Center, UCSF Center for HIV Information

    Researchers at the 2016 Conference on Retroviruses and Opportunistic Infections presented results from a randomized double-blind, double-dummy switch study of TAF/FTC. Over 660 patients with virologic suppression on TDF/FTC-containing 3-drug regimens were either switched to TAF/FTC (200/10 mg...

  • FDA Approves New TAF-Containing Analogue of Complera; Complera Approved for Pediatrics

    March 18, 2016

    • Susa Coffey, MD, AETC National Coordinating Resource Center, UCSF Center for HIV Information

    The FDA has approved a single-pill combination of rilpivirine + emtricitabine + tenofovir alafenamide (TAF); its brand name is Odefsey.

    It is intended for initial treatment of HIV-1-infected persons age 12 years and older whose pretreatment HIV RNA is ≤100,000 copies/mL, or as a substitute...

  • Pyrimethamine Availability

    October 1, 2015

    • Susa Coffey, MD, AETC National Coordinating Resource Center, UCSF Center for HIV Information

    Pyrimethamine is no longer available in retail pharmacies in the United States, though it is available through a commercial specialty pharmacy program (the application process, approval, and delivery of the medication will take at least 2 days; for information on ordering, click...

  • Rilpivirine Updates: Approved for Adolescents; Possible Risk of Depression

    October 1, 2015

    • Susa Coffey, MD, AETC National Coordinating Resource Center, UCSF Center for HIV Information

    The U.S. Food and Drug Administration has approved rilpivirine for use in adolescents 12 to 18 years of age; it is not recommended for younger children. As in adults, it is suggested for use in ARV-naive individuals with HIV RNA levels of ≤100,000 copies/mL. The dosage is 25 mg...

  • Adult and Adolescent Guidelines: Major Changes

    April 28, 2015

    • Susa Coffey, MD, AETC National Coordinating Resource Center, UCSF Center for HIV Information

    The U.S. Department of Health and Human Services has released new treatment guidelines for adults and adolescents, and these contain some important changes. Key among these is a major shakeup in the "Recommended Regimen Options" for initial therapy. 

    Efavirenz/TDF/FTC (Atripla) has...

  • Two New Boosted-PI Coformulations

    February 4, 2015

    • Susa Coffey, MD, AETC National Coordinating Resource Center, UCSF Center for HIV Information

    Two boosted protease inhibitor (PI) coformulations have just been approved by the FDA. These are:

    Darunavir 800 mg + cobicistat 150 mg (Prezcobix), andAtazanavir 300 mg + cobicistat 150 mg (Evotaz)

    In these fixed-dose combinations, cobicistat is used as the pharmacokinetic booster of the PI...

  • Efavirenz Updates: Bone Mineral Density & Suicidality

    August 1, 2014

    • Susa Coffey, MD, AETC National Coordinating Resource Center, UCSF Center for HIV Information
    Efavirenz and Bone Mineral Density

    Persons with HIV infection have a number of risk factors for decreased bone mineral density (BMD), related not just to effects of HIV or resulting illness but also to ART. For example, BMD decreases by as much as 5-6% after initiation of ART, and certain ARVs (...
Day Title
6/23
Intersecting Aspects of HIV and the Social Determinants of Health (Georgia)
Friday, June 23, 2017 - 8:30am EDT (Open Event)
Southeast AETC,
Georgia AIDS Education and Training Center
Event type: Conferences & Events
7/13
Locking Down HIV & HCV: Treating Infectious Diseases in Correctional Settings (Tennessee)
Thursday, July 13, 2017 - 9:00am EDT (Open Event)
Southeast AETC
Event type: Conferences & Events
9/29
The 13th Annual National Conference on HIV/AIDS & Aging (Massachusetts)
Friday, September 29, 2017 - 8:00am EDT (Open Event)
New England AETC
Event type: Conferences & Events
10/23
National Day of Action to End Violence Against Women with HIV (National)
Monday, October 23, 2017 (All day) (Open Event)
Event type: Awareness Days
Day Title
6/5
HIV Long-Term Survivors Day (National)
Monday, June 5, 2017 (All day) (Open Event)
Event type: Awareness Days
6/4
International Association of Providers of AIDS Care (IAPAC) International Conference on HIV Treatment Adherence (Florida)
Sunday, June 4, 2017 (All day) to Tuesday, June 6, 2017 (All day) (Open Event)
Event type: Conferences & Events
5/22
2017 National Latino HIV and Hepatitis C Conference (National, Texas)
Monday, May 22, 2017 (All day) to Wednesday, May 24, 2017 (All day) (Open Event)
Valley AIDS Council,
South Central AETC
Event type: Conferences & Events
3/24
American Pharmacists Association Annual Meeting and Exposition 2017 (California)
Friday, March 24, 2017 (All day) to Monday, March 27, 2017 (All day) (Open Event)
Event type: Conferences & Events
3/7
Pediatric HIV/AIDS Training Course (Tennessee)
Tuesday, March 7, 2017 (All day) to Wednesday, March 8, 2017 (All day) (Open Event)
Event type: Conferences & Events
2/13
CROI 2017: Seattle (Washington)
Monday, February 13, 2017 (All day) to Thursday, February 16, 2017 (All day) (Open Event)
International Antiviral Society-USA
Event type: Conferences & Events