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National Clinician Consultation Center

University of California, San Francisco
Department of Family and Community Medicine
Zuckerberg San Francisco General Hospital, 1001 Potrero Avenue, Building 20, Ward 2203
San Francisco, CA 94110

phone: (628) 206-8700
fax: (415) 476-3454

NCCC Online

The National Clinician Consultation Center provides health care providers with a national resource to obtain timely and appropriate responses to clinical questions related to treatment of persons with HIV infection and possible health care worker exposure to HIV and other bloodborne pathogens.

HIV Management Service (Warmline): 800-933-3413

Monday-Friday, 9 am - 8 pm ET. For questions about HIV/AIDS, including antiretroviral therapy, HIV clinical manifestations, and laboratory evaluation.

electronic Clinician Consultation Service (e-CCS Online Consultation)

For submission of questions about HIV management and case-tracking online. Register at

Post-Exposure Prophylaxis Hotline (PEPline): 888-HIV-4911 (888-448-4911)

Hours of operation for occupational PEP consultation are 11 a.m. – 8 p.m. ET (seven days a week). If you are trying to reach us regarding an occupational PEP question outside of these hours, please check out our PEP Quick Guide for Occupational Exposures.  

Hours of operation for non-occupational PEP consultation are 9 a.m. – 8 p.m. ET Monday – Friday, and 11 a.m. – 8 p.m. ET on weekends & holidays.  

Perinatal HIV Consultation and Referral Services (Perinatal HIV Hotline): 888-HIV-8765 (888-448-8765)

For questions about the care of HIV-infected pregnant women as well as indications and interpretations of rapid and standard HIV tests. Available 24 hours/day, 7 days/week.

Pre-Exposure Prophylaxis Service (PrEPline): 855-HIV-PrEP (855-448-7737)

For questions about the appropriateness, administration, and laboratory and follow-up procedures of pre-exposure prophylaxis as a prevention tool.

Clinical Substance Use Consultation (Substance Use Warmline): 855-300-3595

The CCC offers free and confidential peer-to-peer telephone consultation focusing on substance use evaluation and management for primary care clinicians through the Substance Use Warmline at (855) 300-3595. Consultation is available Monday - Friday, 9 am - 8 pm ET, from addiction medicine-certified physicians, clinical pharmacists, and nurses with expertise in pharmacotherapy options for opioid use. Voicemail is available 24 hours a day.

Hepatitis C Management: 844-437-4636 or 844-(HEP-INFO)

Monday-Friday; 9 am - 8 pm ET. Call us for clinician-to-clinician advice on hepatitis C monoinfection management, from testing and treatment initiation to management of advanced disease.


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