2025 US Public Health Service Guidelines for the Management of Occupational Exposures to Human Immunodeficiency Virus (HIV) and Recommendations for Post-exposure Prophylaxis (PEP) in Healthcare Settings

Description:

These guidelines update the 2013 “Updated US Public Health Service (PHS) Guidelines for the Management of Occupational Exposures to HIV and Recommendations for PEP,” hereafter referred to as the 2013 PHS Guidelines.1,2 The availability of new medication options, new information on the window of detection for different HIV tests, and the risk of transmission from people with undetectable viral loads prompted this update. The primary intended audience for these recommendations remains anyone involved in the provision of HIV post-exposure management to healthcare personnel (HCP).