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Non-Occupational Post-Exposure Prophylaxis (nPEP) Toolkit

image of PEP poster

This toolkit is a collaborative product of the AETC organizations:

  • Program Rural Health Committee
  • AETC National Clinician Consultation Center
  • Georgia Department of Public Health
  • International Association of Forensic Nurses
  • National Center for Medical-Legal Partnership


  • Start post-exposure prophylaxis (PEP) as soon as possible after a known or possible HIV exposure (occupational or non-occupational sexual and injection exposures)
  • These resources provide step-by-step instructions for the medical care of persons following possible sexual HIV exposure
  • The U.S. Food and Drug Administration (FDA) alerted the public on 5/18/18 that cases of neural tube birth defects have been reported in babies born to women with HIV who were treated with dolutegravir prior to conception. Providers may call the PEPline at (888) 448-4911 if they have questions or need additional support.

Be part of a national project to improve health care providers’ readiness to respond to potential sexual exposures to HIV by completing our survey!

Toolkit Materials

These materials were developed to be used in clinical settings to raise awareness and offer detailed guidance. All additional materials can be downloaded and printed as needed. 

The State of nPEP in Rural America: Clinician Perspectives

ShareSpot: The AETC Blog

Patients to Policy Story

National Center for Medical-Legal Partnership: Patients-to-Policy Story Series

World AIDS Day 2017 PEP Interview with Dr. Donna Sweet (YouTube)

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