Morbidity and Mortality in HCV Co-infected People with HIV

HIV HCV Curriculum Logo

This lesson focuses on the impact of HIV infection and HCV infection outcomes in co-infected persons of color. The causes of morbidity and mortality associated with HIV/HCV co-infection are also discussed. 



Download Slides 

References

  1. de Lédinghen V, Barreiro P, Foucher J, et al. Liver fibrosis on account of chronic hepatitis C is more severe in HIV-positive than HIV-negative patients despite antiretroviral therapy. J Viral Hepat. 2008 Jun;15(6):427-33. PubMed PMID: 18221303.
  2. Kirk GD, Mehta SH, Astemborski J, et al. HIV, age, and the severity of hepatitis C virus-related liver disease: a cohort study. Ann Intern Med. 2013 May 7;158(9):658-66. PubMed PMID: 23440167.
  3. Fierer DS, Dieterich DT, Fiel MI, et al. Rapid progression to decompensated cirrhosis, liver transplant, and death in HIV-infected men after primary hepatitis C virus infection. Clin Infect Dis. 2013 Apr;56(7):1038-43. PubMed PMID: 23264364.
  4. Graham CS, Baden LR, Yu E, et al. Influence of human immunodeficiency virus infection on the course of hepatitis C virus infection: a meta-analysis. Clin Infect Dis. 2001 Aug 15;33(4):562-9. PubMed PMID: 11462196.
  5. Slide modified from: Kim AY. Challenges in the Management and Treatment of HIV/HCV Coinfection. Slide 9: Nonhepatic effects of HCV in HIV. Presented at: An Advanced CME Live Course in HIV Pathogenesis, Antiretrovirals, and Other Selected Issues in HIV Disease Management, Washington, DC. 4/15/2016. 
  6. Borges AH, Hoy J, Florence E, et al. Antiretrovirals, Fractures, and Osteonecrosis in a Large European HIV Cohort. In: Program and abstracts of the 23rd Conference on Retroviruses and Opportunistic Infections; Feb 22-25, 2016; Boston. Abstract 46.
  7. Kovari H, Weber R,  Calmy AL, et al. Hepatitis C and the Risk of Non-Liver-Related Morbidity and Mortality in HIV+ Persons. In: Program and abstracts of the 23rd Conference on Retroviruses and Opportunistic Infections; Feb 22-25, 2016; Boston. Abstract 612.
  8. Berenguer J, Alvaro-Meca A, Diaz A, Micheloud D, Resino S. Stroke in HIV-Infected Patients in the Combination Antiretroviral Therapy Era
    7.In: Program and abstracts of the 23rd Conference on Retroviruses and Opportunistic Infections; Feb 22-25, 2016; Boston. Abstract 639. 
  9. Clement ME, Park L, Navar AM, et al. Cardiovascular Disease Risk Model Comparison and Development in HIV-Infected Veterans. In: Program and abstracts of the 23rd Conference on Retroviruses and Opportunistic Infections; Feb 22-25, 2016; Boston. Abstract 642. 
  10. Shire N, Sherman K. Epidemiology of Hepatitis C Virus. A Battle on New Frontiers. Gastroenterology Clinics of North America [serial online]. December 1, 2015;44(Hepatitis C Virus: The Next Epidemic):699-716. Available from: ScienceDirect, Ipswich, MA. Accessed June 20, 2017.
  11. Platt L, Easterbrook P, Vickerman P, et al. Articles: Prevalence and burden of HCV co-infection in people living with HIV: a global systematic review and meta-analysis. The Lancet Infectious Diseases [serial online]. July 1, 2016;16:797-808. Available from: ScienceDirect, Ipswich, MA. Accessed June 20, 2017.
  12. Merriman, R.B. Nonalcoholic fatty liver disease and HIV infection. Curr HIV/AIDS Rep (2006) 3: 113.